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It is currently admin-istered every 2 weeks with doses varying between 15 and 60 U/kg/infusion. Unfortunately, there is signi? cantinterobserver variability in the assessment of aleak at extubation: it is dependent upon headposition, sedation, and presence of secretions inthe airway.

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This recognition of self (autoantigen) by the T cell is the result of the selectionprocess mentioned above. Fluctuations in alertness and cogni-tive functions, early onset visual hallucinations, andParkinson’s disease symptoms all suggest Lewy bodydementia

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18.8 The importance of colon distension during CT colonogra-phy. Interms of PaCO2 levels, the threshold for the CPAPgroup was 65 mmHg (both for intubation and forextubation), while it was 50 mmHg for extuba-tion in the control group (showing that even inthe standard group, higher-than-“normal” PaCO2levels are currently being accepted).

Any dose not administered at the recommended ageshould be administered at a subsequent visit, when indicated and feasible.